Fiber medicine

A new graphene fiber electrode could help develop advanced therapies in bioelectronic medicine

An international team of researchers from the ARC Center of Excellence for Electromaterials Science (ACES) and the University of Houston has helped advance electroceutical research for the treatment of diseases such as rheumatoid arthritis, colitis and sepsis.

Coating steps of extruded Pt-rGO electrodes. Item Picture

The team has published their latest paper, which builds on previous studies in which the team reported on the ‘Sutrode’ – a graphene-based electrode created using the fabrication technique known as fiber wet spinning name.

Professor Gordon Wallace, Director of ACES at UOW, co-author of the paper, explained how special the Sutrode could be by combining the properties of a suture (which can be tied) and a an electrode (with high electrical conductivity). These sutrodes can be integrated into delicate neural systems to monitor neural activity.

“This work has wide implications for the regulation of spleen function, in particular the effective regulation of the immune response for the electroceutical treatment of a range of diseases,” Professor Wallace said. “We highlighted the ongoing need to develop systems with increased fidelity and spatial resolution. This will not only bring practical applications to the fore, but will enable the inaccessible exploration of the human neural system.

The work captured in the new paper also emphasizes the ability to simultaneously interrogate all four individual neural inputs in the spleen.

Professor Mario Romero-Ortega, Professor of Bioengineering and Biomedical Sciences at the University of Houston, said: “The Sutrode’s flexibility and superb sensitivity allow us to expand our understanding of how the nervous system controls major organs of the body, a critical stage. towards the development of advanced therapies in bioelectronic drugs”. “Our collaborative work revealed that the spleen is controlled by different terminal nerves and that the sutrode can be used to control them, increasing the precision with which the function of this organ can be modulated.”